Paul L Bollyky Selected Research

Spasm (Spasms)

1/2022	Oral hymecromone decreases hyaluronan in human study participants.
10/2019	4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition.
2/2016	Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization.
1/2015	4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer.

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Paul L Bollyky Research Topics

Disease

18	Infections 03/2024 - 07/2007
18	Inflammation (Inflammations) 01/2023 - 09/2009
12	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 02/2021 - 02/2010
10	Wounds and Injuries (Trauma) 01/2022 - 01/2015
8	Cystic Fibrosis (Mucoviscidosis) 03/2024 - 11/2015
7	Fibrosis (Cirrhosis) 10/2021 - 01/2017
5	Bacterial Infections (Bacterial Infection) 01/2024 - 01/2018
5	COVID-19 01/2023 - 08/2021
4	Spasm (Spasms) 01/2022 - 01/2015
4	Cicatrix (Scar) 10/2021 - 11/2019
3	Neoplasms (Cancer) 05/2024 - 01/2015
3	Type 2 Diabetes Mellitus (MODY) 11/2023 - 01/2019
3	Persistent Infection 07/2022 - 01/2020
3	Inborn Genetic Diseases (Disease, Hereditary) 04/2022 - 08/2021
3	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2022 - 01/2019
3	Pulmonary Hypertension 01/2022 - 10/2017
3	Hypersensitivity (Allergy) 01/2021 - 01/2018
3	Lung Injury 01/2019 - 01/2017
3	Multiple Sclerosis 01/2017 - 01/2015
2	Wound Infection (Wound Infections) 12/2023 - 07/2023
2	Weight Gain 11/2023 - 03/2023
2	Obesity 11/2023 - 03/2023
2	Lung Diseases (Lung Disease) 01/2022 - 01/2019
1	Communicable Diseases (Infectious Diseases) 05/2024
1	Neuroinflammatory Diseases 02/2024
1	Sepsis (Septicemia) 01/2023
1	Necrosis 04/2022
1	Febrile Neutropenia 01/2022
1	Superinfection 01/2022
1	Breast Neoplasms (Breast Cancer) 02/2021
1	Erythema 01/2021
1	Pain (Aches) 01/2021
1	Suppurative Otitis Media 01/2020
1	Ureteral Obstruction 01/2020
1	Neoplasm Metastasis (Metastasis) 01/2020
1	Ischemia 01/2020
1	Hemorrhage 01/2019
1	Body Weight (Weight, Body) 01/2019
1	Autoimmune Diseases (Autoimmune Disease) 01/2019
1	Emphysema 01/2019
1	Hyperglycemia 01/2019

Drug/Important Bio-Agent (IBA)

28	Hyaluronic Acid (Hyaluronan)IBA 11/2023 - 07/2007
10	CytokinesIBA 10/2021 - 01/2017
8	HymecromoneIBA 11/2023 - 01/2015
8	Interleukin-10 (Interleukin 10)IBA 01/2022 - 01/2013
6	Anti-Bacterial Agents (Antibiotics)IBA 03/2024 - 01/2020
6	Proteins (Proteins, Gene)FDA Link 04/2022 - 01/2017
6	GlycosaminoglycansIBA 01/2022 - 08/2014
4	PolymersIBA 01/2023 - 11/2015
4	DNA (Deoxyribonucleic Acid)IBA 04/2022 - 01/2020
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 02/2010
4	CollagenIBA 10/2021 - 11/2019
3	Insulin (Novolin)FDA Link 11/2023 - 12/2018
3	Hyaluronoglucosaminidase (Hyaluronidase)FDA Link 04/2022 - 08/2021
3	Deoxyribonucleases (DNase)FDA Link 04/2022 - 08/2021
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 01/2012
2	Interleukin-2 (IL2)IBA 02/2024 - 01/2021
2	GoldIBA 11/2023 - 05/2023
2	Cell-Free Nucleic AcidsIBA 01/2023 - 01/2022
2	erucylphosphocholineIBA 01/2022 - 09/2015
2	ChemokinesIBA 01/2022 - 11/2015
2	HydrogelsIBA 01/2021 - 01/2019
2	InterleukinsIBA 01/2020 - 02/2010
2	Heparitin Sulfate (Heparan Sulfate)IBA 01/2020 - 12/2018
2	Hyaluronan SynthasesIBA 01/2019 - 10/2017
2	Polysaccharides (Glycans)IBA 02/2016 - 10/2015
1	Monoclonal AntibodiesIBA 02/2024
1	Chimeric Antigen ReceptorsIBA 02/2024
1	Investigational DrugsIBA 01/2024
1	EndotoxinsIBA 01/2023
1	Versicans (Versican)IBA 04/2022
1	Cell Surface ReceptorsIBA 01/2022
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2021
1	Minocycline (Cyclops)FDA LinkGeneric 01/2021
1	phosphomannopentaose sulfateIBA 01/2020
1	Dihydrotachysterol (AT 10)IBA 01/2020
1	4-methylumbelliferyl glucuronideIBA 10/2019
1	Antiviral Agents (Antivirals)IBA 01/2019
1	Adenosine (Adenocard)FDA LinkGeneric 01/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	AutoantigensIBA 01/2019
1	thiocyanateIBA 01/2019
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2019
1	Adrenergic Agents (Adrenergic Drugs)IBA 01/2019
1	Heparin (Liquaemin)FDA LinkGeneric 01/2019
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2017
1	Immunoglobulin E (IgE)IBA 01/2017
1	OvalbuminIBA 01/2017

Therapy/Procedure

8	Therapeutics 05/2024 - 01/2018
7	Phage Therapy 01/2024 - 01/2018
3	Glycemic Control 11/2023 - 01/2019
2	Precision Medicine 11/2023 - 05/2023
2	Reoperation 01/2020 - 03/2011
1	Photothermal Therapy 05/2024
1	Surgical Amputation (Amputations) 01/2021
1	Injections 01/2021
1	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2021
1	Replacement Arthroplasty 01/2020
1	Oral Administration 10/2019
1	Arthroplasty 01/2018